Find Copa Airlines flights from Mexico City (MEX) to Santiago de Chile (SCL) from USD 522*

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Best prices on Mexico City to Santiago de Chile flights

Oct 2026
FromUSD 851*
Viewed 1 day ago
Round trip/Economy
Nov 2026
FromUSD 851*
Viewed 1 day ago
Round trip/Economy
Dec 2026
FromUSD 522*
Viewed 13 hours ago
Round trip/Economy
cmp-daily-histogram-bars-legend-min-price-aria-label USD 851
Displaying fares for October-2026
  • MEX–SCL, Oct 29, 2026 – Nov 18, 2026: From USD 851
    29

    Thu

    OCT

  • MEX–SCL: cmp-view-offers-disclaimer. Check availability
    30

    Fri

  • MEX–SCL, Oct 31, 2026 – Nov 11, 2026: From USD 851
    31

    Sat

  • MEX–SCL, Nov 01, 2026 – Nov 28, 2026: From USD 851
    01

    Sun

    NOV

  • MEX–SCL: cmp-view-offers-disclaimer. Check availability
    02

    Mon

  • MEX–SCL: cmp-view-offers-disclaimer. Check availability
    03

    Tue

  • MEX–SCL, Nov 04, 2026 – Nov 13, 2026: From USD 898
    04

    Wed

  • MEX–SCL: cmp-view-offers-disclaimer. Check availability
    05

    Thu

  • MEX–SCL: cmp-view-offers-disclaimer. Check availability
    06

    Fri

  • MEX–SCL: cmp-view-offers-disclaimer. Check availability
    07

    Sat

  • MEX–SCL: cmp-view-offers-disclaimer. Check availability
    08

    Sun

  • MEX–SCL: cmp-view-offers-disclaimer. Check availability
    09

    Mon

  • MEX–SCL: cmp-view-offers-disclaimer. Check availability
    10

    Tue

  • MEX–SCL: cmp-view-offers-disclaimer. Check availability
    11

    Wed

  • MEX–SCL: cmp-view-offers-disclaimer. Check availability
    12

    Thu

  • MEX–SCL: cmp-view-offers-disclaimer. Check availability
    13

    Fri

  • MEX–SCL: cmp-view-offers-disclaimer. Check availability
    14

    Sat

  • MEX–SCL: cmp-view-offers-disclaimer. Check availability
    15

    Sun

  • MEX–SCL: cmp-view-offers-disclaimer. Check availability
    16

    Mon

  • MEX–SCL: cmp-view-offers-disclaimer. Check availability
    17

    Tue

  • MEX–SCL: cmp-view-offers-disclaimer. Check availability
    18

    Wed

  • MEX–SCL: cmp-view-offers-disclaimer. Check availability
    19

    Thu

  • MEX–SCL: cmp-view-offers-disclaimer. Check availability
    20

    Fri

  • MEX–SCL, Nov 21, 2026 – Nov 26, 2026: From USD 851
    21

    Sat

  • MEX–SCL, Nov 22, 2026 – Nov 26, 2026: From USD 851
    22

    Sun

  • MEX–SCL: cmp-view-offers-disclaimer. Check availability
    23

    Mon

  • MEX–SCL: cmp-view-offers-disclaimer. Check availability
    24

    Tue

  • MEX–SCL: cmp-view-offers-disclaimer. Check availability
    25

    Wed

  • MEX–SCL: cmp-view-offers-disclaimer. Check availability
    26

    Thu

  • MEX–SCL: cmp-view-offers-disclaimer. Check availability
    27

    Fri

  • MEX–SCL: cmp-view-offers-disclaimer. Check availability
    28

    Sat

    • FromUSD 851-USD 898

    *Restrictions apply; please see Terms & Conditions.

    Round-trip fares from Mexico City to Santiago de Chile

    USD
    Round-trip fares from Mexico City to Santiago de Chile
    From
    To
    Fare Type
    Dates
    Price
    Mexico City (MEX)Santiago de Chile (SCL)Round trip
    /
    Economy    		Dec 31, 2026 - Mar 10, 2027

    From

    USD 522

    Viewed 13 hours ago

    Mexico City (MEX)Santiago de Chile (SCL)Round trip
    /
    Economy    		Dec 29, 2026 - Mar 10, 2027

    From

    USD 845

    Viewed 12 hours ago

    Mexico City (MEX)Santiago de Chile (SCL)Round trip
    /
    Economy    		Dec 08, 2026 - Dec 25, 2026

    From

    USD 845

    Viewed 9 hours ago

    Mexico City (MEX)Santiago de Chile (SCL)Round trip
    /
    Economy    		Jun 03, 2027 - Jun 10, 2027

    From

    USD 819

    Viewed 1 day ago

    Mexico City (MEX)Santiago de Chile (SCL)Round trip
    /
    Economy    		Nov 22, 2026 - Nov 26, 2026

    From

    USD 851

    Viewed 1 day ago

    *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
    *Restrictions apply; please see Terms & Conditions.

    Destination facts

    Destination airports
    • Comodoro Arturo Merino Benítez International Airport (SCL)
    Copa Airlines hub

    Hub of the Americas® in Panama

    Destination FAQs

    Which country or territory is the destination on this page in?

    Destination country or territory: Chile.

    How do I identify the arrival airport?

    Check the name and code of the arrival airport in your selected itinerary.

    Where is the Hub of the Americas®?

    Copa Airlines’ Hub of the Americas® is in Panama.

    More options from Mexico City, departing from Felipe Angeles International Airport

    USD

    **Restrictions apply; please see Terms & Conditions.

     

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