Find Copa Airlines flights from San Francisco (SFO) to Guayaquil (GYE) from USD378*
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Best prices on San Francisco to Guayaquil flights
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Best airfares from San Francisco to Guayaquil flights
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From | To | Fare Type | Dates | Price |
|---|---|---|---|---|
| San Francisco (SFO) | Guayaquil (GYE) | Round trip / Economy | Apr 21, 2026 - Apr 29, 2026 | From USD378 Viewed 1 day ago |
| San Francisco (SFO) | Guayaquil (GYE) | Round trip / Economy | Apr 22, 2026 - Apr 29, 2026 | From USD378 Viewed 1 day ago |
| San Francisco (SFO) | Guayaquil (GYE) | Round trip / Economy | Apr 23, 2026 - Apr 29, 2026 | From USD437 Viewed 1 day ago |
| San Francisco (SFO) | Guayaquil (GYE) | Round trip / Economy | May 14, 2026 - Jun 02, 2026 | From USD510 Viewed 13 hours ago |
| San Francisco (SFO) | Guayaquil (GYE) | Round trip / Economy | Apr 12, 2026 - Apr 17, 2026 | From USD674 Viewed 15 hours ago |
*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.
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