Find Copa Airlines flights from San Francisco (SFO) to Medellin (MDE) from USD 651*

Promo Code

Restrictions apply; please see Terms & Conditions.

Best prices on San Francisco to Medellin flights

Aug 2026
FromUSD 651*
Viewed 23 hours ago
Round trip/Economy
Sep 2026
FromUSD 651*
Viewed 5 hours ago
Round trip/Economy
Oct 2026
FromUSD 651*
Viewed 14 hours ago
Round trip/Economy
cmp-daily-histogram-bars-legend-min-price-aria-label USD 651
cmp-daily-histogram-bars-legend-max-price-aria-label USD 873
Displaying fares for August-2026
  • SFO–MDE, Aug 23, 2026 – Aug 26, 2026: From USD 671
    23

    Sun

    AUG

  • SFO–MDE, Aug 24, 2026 – Aug 29, 2026: From USD 756
    24

    Mon

  • SFO–MDE: cmp-view-offers-disclaimer. Check availability
    25

    Tue

  • SFO–MDE, Aug 26, 2026 – Sep 06, 2026: From USD 696
    26

    Wed

  • SFO–MDE, Aug 27, 2026 – Sep 01, 2026: From USD 696
    27

    Thu

  • SFO–MDE, Aug 28, 2026 – Sep 18, 2026: From USD 651
    28

    Fri

  • SFO–MDE, Aug 29, 2026 – Sep 18, 2026: From USD 696
    29

    Sat

  • SFO–MDE, Aug 30, 2026 – Sep 04, 2026: From USD 741
    30

    Sun

  • SFO–MDE: cmp-view-offers-disclaimer. Check availability
    31

    Mon

  • SFO–MDE: cmp-view-offers-disclaimer. Check availability
    01

    Tue

    SEP

  • SFO–MDE, Sep 02, 2026 – Sep 08, 2026: From USD 786
    02

    Wed

  • SFO–MDE: cmp-view-offers-disclaimer. Check availability
    03

    Thu

  • SFO–MDE: cmp-view-offers-disclaimer. Check availability
    04

    Fri

  • SFO–MDE: cmp-view-offers-disclaimer. Check availability
    05

    Sat

  • SFO–MDE, Sep 06, 2026 – Sep 14, 2026: From USD 841
    06

    Sun

  • SFO–MDE, Sep 07, 2026 – Sep 14, 2026: From USD 873
    07

    Mon

  • SFO–MDE, Sep 08, 2026 – Sep 15, 2026: From USD 741
    08

    Tue

  • SFO–MDE, Sep 09, 2026 – Sep 16, 2026: From USD 651
    09

    Wed

  • SFO–MDE: cmp-view-offers-disclaimer. Check availability
    10

    Thu

  • SFO–MDE: cmp-view-offers-disclaimer. Check availability
    11

    Fri

  • SFO–MDE: cmp-view-offers-disclaimer. Check availability
    12

    Sat

  • SFO–MDE, Sep 13, 2026 – Sep 16, 2026: From USD 651
    13

    Sun

  • SFO–MDE: cmp-view-offers-disclaimer. Check availability
    14

    Mon

  • SFO–MDE, Sep 15, 2026 – Sep 21, 2026: From USD 696
    15

    Tue

  • SFO–MDE: cmp-view-offers-disclaimer. Check availability
    16

    Wed

  • SFO–MDE: cmp-view-offers-disclaimer. Check availability
    17

    Thu

  • SFO–MDE: cmp-view-offers-disclaimer. Check availability
    18

    Fri

  • SFO–MDE, Sep 19, 2026 – Sep 20, 2026: From USD 741
    19

    Sat

  • SFO–MDE: cmp-view-offers-disclaimer. Check availability
    20

    Sun

  • SFO–MDE: cmp-view-offers-disclaimer. Check availability
    21

    Mon

  • SFO–MDE: cmp-view-offers-disclaimer. Check availability
    22

    Tue

    • FromUSD 651-USD 873

    *Restrictions apply; please see Terms & Conditions.

    Best airfares from San Francisco to Medellin flights

    USD
    Best airfares from San Francisco to Medellin flights
    From
    To
    Fare Type
    Dates
    Price
    San Francisco (SFO)Medellin (MDE)Round trip
    /
    Economy    		Sep 30, 2026 - Oct 04, 2026

    From

    USD 651

    Viewed 22 hours ago

    San Francisco (SFO)Medellin (MDE)Round trip
    /
    Economy    		Nov 08, 2026 - Nov 16, 2026

    From

    USD 651

    Viewed 19 hours ago

    San Francisco (SFO)Medellin (MDE)Round trip
    /
    Economy    		Sep 13, 2026 - Sep 16, 2026

    From

    USD 651

    Viewed 14 hours ago

    San Francisco (SFO)Medellin (MDE)Round trip
    /
    Economy    		Oct 29, 2026 - Nov 11, 2026

    From

    USD 651

    Viewed 3 hours ago

    San Francisco (SFO)Medellin (MDE)Round trip
    /
    Economy    		Oct 29, 2026 - Nov 12, 2026

    From

    USD 651

    Viewed 3 hours ago

    *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
    *Restrictions apply; please see Terms & Conditions.

    Find more related flights

    Our App

    Download the Copa Airlines App now and buy tickets, manage your reservations, access to your ConnectMiles account and much more.

    Copa Airlines App - App Store Copa Airlines App - Play Store Copa Airlines App - Huawei Store Copa Airlines app

    Explore Copa Airlines' Top-Pick Destinations