Find Copa Airlines flights from Santo Domingo (SDQ) to Guayaquil (GYE) from USD399*
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Best prices on Santo Domingo to Guayaquil flights
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Best airfares from Santo Domingo to Guayaquil flights
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From | To | Fare Type | Dates | Price |
|---|---|---|---|---|
| Santo Domingo (SDQ) | Guayaquil (GYE) | Round trip / Economy | Apr 11, 2026 - Apr 27, 2026 | From USD399 Viewed 5 hours ago |
| Santo Domingo (SDQ) | Guayaquil (GYE) | Round trip / Economy | Apr 11, 2026 - Apr 28, 2026 | From USD399 Viewed 5 hours ago |
| Santo Domingo (SDQ) | Guayaquil (GYE) | Round trip / Economy | Apr 03, 2026 - Apr 18, 2026 | From USD399 Viewed 9 hours ago |
| Santo Domingo (SDQ) | Guayaquil (GYE) | Round trip / Economy | Jul 16, 2026 - Sep 01, 2026 | From USD399 Viewed 7 hours ago |
| Santo Domingo (SDQ) | Guayaquil (GYE) | Round trip / Economy | Jul 17, 2026 - Sep 01, 2026 | From USD399 Viewed 7 hours ago |
*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.
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