Find Copa Airlines flights from Guatemala (GUA) to Medellin (MDE) from USD 416*

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Restrictions apply; please see Terms & Conditions.

Best prices on Guatemala to Medellin flights

Sep 2026
FromUSD 416*
Viewed 1 day ago
Round trip/Economy
Oct 2026
FromUSD 416*
Viewed 1 day ago
Round trip/Economy
Nov 2026
FromUSD 416*
Viewed 1 day ago
Round trip/Economy
cmp-daily-histogram-bars-legend-min-price-aria-label USD 416
cmp-daily-histogram-bars-legend-max-price-aria-label USD 678
Displaying fares for September-2026
  • GUA–MDE: cmp-view-offers-disclaimer. Check availability
    13

    Sun

    SEP

  • GUA–MDE: cmp-view-offers-disclaimer. Check availability
    14

    Mon

  • GUA–MDE, Sep 15, 2026 – Sep 19, 2026: From USD 490
    15

    Tue

  • GUA–MDE, Sep 16, 2026 – Sep 18, 2026: From USD 490
    16

    Wed

  • GUA–MDE, Sep 17, 2026 – Sep 20, 2026: From USD 658
    17

    Thu

  • GUA–MDE, Sep 18, 2026 – Sep 25, 2026: From USD 490
    18

    Fri

  • GUA–MDE, Sep 19, 2026 – Sep 22, 2026: From USD 445
    19

    Sat

  • GUA–MDE, Sep 20, 2026 – Sep 24, 2026: From USD 416
    20

    Sun

  • GUA–MDE, Sep 21, 2026 – Sep 25, 2026: From USD 416
    21

    Mon

  • GUA–MDE, Sep 22, 2026 – Sep 29, 2026: From USD 416
    22

    Tue

  • GUA–MDE, Sep 23, 2026 – Sep 26, 2026: From USD 445
    23

    Wed

  • GUA–MDE, Sep 24, 2026 – Sep 28, 2026: From USD 520
    24

    Thu

  • GUA–MDE, Sep 25, 2026 – Sep 29, 2026: From USD 416
    25

    Fri

  • GUA–MDE, Sep 26, 2026 – Sep 29, 2026: From USD 416
    26

    Sat

  • GUA–MDE, Sep 27, 2026 – Oct 01, 2026: From USD 537
    27

    Sun

  • GUA–MDE, Sep 28, 2026 – Sep 30, 2026: From USD 537
    28

    Mon

  • GUA–MDE: cmp-view-offers-disclaimer. Check availability
    29

    Tue

  • GUA–MDE, Sep 30, 2026 – Oct 04, 2026: From USD 537
    30

    Wed

  • GUA–MDE, Oct 01, 2026 – Oct 07, 2026: From USD 563
    01

    Thu

    OCT

  • GUA–MDE, Oct 02, 2026 – Oct 10, 2026: From USD 416
    02

    Fri

  • GUA–MDE, Oct 03, 2026 – Oct 30, 2026: From USD 555
    03

    Sat

  • GUA–MDE: cmp-view-offers-disclaimer. Check availability
    04

    Sun

  • GUA–MDE: cmp-view-offers-disclaimer. Check availability
    05

    Mon

  • GUA–MDE, Oct 06, 2026 – Oct 16, 2026: From USD 416
    06

    Tue

  • GUA–MDE, Oct 07, 2026 – Oct 15, 2026: From USD 678
    07

    Wed

  • GUA–MDE: cmp-view-offers-disclaimer. Check availability
    08

    Thu

  • GUA–MDE: cmp-view-offers-disclaimer. Check availability
    09

    Fri

  • GUA–MDE: cmp-view-offers-disclaimer. Check availability
    10

    Sat

  • GUA–MDE: cmp-view-offers-disclaimer. Check availability
    11

    Sun

  • GUA–MDE: cmp-view-offers-disclaimer. Check availability
    12

    Mon

    • FromUSD 416-USD 678

    *Restrictions apply; please see Terms & Conditions.

    Best airfares from Guatemala to Medellin flights

    USD
    Best airfares from Guatemala to Medellin flights
    From
    To
    Fare Type
    Dates
    Price
    Guatemala (GUA)Medellin (MDE)Round trip
    /
    Economy    		Feb 12, 2027 - Feb 15, 2027

    From

    USD 416

    Viewed 16 hours ago

    Guatemala (GUA)Medellin (MDE)Round trip
    /
    Economy    		Oct 06, 2026 - Oct 10, 2026

    From

    USD 416

    Viewed 11 hours ago

    Guatemala (GUA)Medellin (MDE)Round trip
    /
    Economy    		Oct 06, 2026 - Oct 16, 2026

    From

    USD 416

    Viewed 21 hours ago

    Guatemala (GUA)Medellin (MDE)Round trip
    /
    Economy    		Oct 15, 2026 - Oct 20, 2026

    From

    USD 416

    Viewed 1 day ago

    Guatemala (GUA)Medellin (MDE)Round trip
    /
    Economy    		Sep 20, 2026 - Sep 24, 2026

    From

    USD 416

    Viewed 1 day ago

    *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
    *Restrictions apply; please see Terms & Conditions.

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