Find Copa Airlines flights from Guatemala (GUA) to Medellin (MDE) from USD 380*

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Restrictions apply; please see Terms & Conditions.

Best prices on Guatemala to Medellin flights

Oct 2026
FromUSD 381*
Viewed 57 minutes ago
Round trip/Economy
Nov 2026
FromUSD 381*
Viewed 3 hours ago
Round trip/Economy
Dec 2026
FromUSD 427*
Viewed 8 hours ago
Round trip/Economy
cmp-daily-histogram-bars-legend-min-price-aria-label USD 381
cmp-daily-histogram-bars-legend-max-price-aria-label USD 799
Displaying fares for October-2026
  • GUA–MDE: cmp-view-offers-disclaimer. Check availability
    29

    Thu

    OCT

  • GUA–MDE, Oct 30, 2026 – Nov 07, 2026: From USD 381
    30

    Fri

  • GUA–MDE: cmp-view-offers-disclaimer. Check availability
    31

    Sat

  • GUA–MDE: cmp-view-offers-disclaimer. Check availability
    01

    Sun

    NOV

  • GUA–MDE: cmp-view-offers-disclaimer. Check availability
    02

    Mon

  • GUA–MDE, Nov 03, 2026 – Nov 06, 2026: From USD 393
    03

    Tue

  • GUA–MDE, Nov 04, 2026 – Nov 07, 2026: From USD 451
    04

    Wed

  • GUA–MDE, Nov 05, 2026 – Nov 11, 2026: From USD 381
    05

    Thu

  • GUA–MDE, Nov 06, 2026 – Nov 27, 2026: From USD 381
    06

    Fri

  • GUA–MDE, Nov 07, 2026 – Nov 10, 2026: From USD 393
    07

    Sat

  • GUA–MDE, Nov 08, 2026 – Nov 24, 2026: From USD 445
    08

    Sun

  • GUA–MDE, Nov 09, 2026 – Nov 11, 2026: From USD 481
    09

    Mon

  • GUA–MDE, Nov 10, 2026 – Nov 14, 2026: From USD 533
    10

    Tue

  • GUA–MDE, Nov 11, 2026 – Nov 15, 2026: From USD 520
    11

    Wed

  • GUA–MDE, Nov 12, 2026 – Dec 02, 2026: From USD 445
    12

    Thu

  • GUA–MDE, Nov 13, 2026 – Dec 02, 2026: From USD 493
    13

    Fri

  • GUA–MDE, Nov 14, 2026 – Dec 02, 2026: From USD 440
    14

    Sat

  • GUA–MDE, Nov 15, 2026 – Dec 10, 2026: From USD 482
    15

    Sun

  • GUA–MDE, Nov 16, 2026 – Nov 19, 2026: From USD 381
    16

    Mon

  • GUA–MDE, Nov 17, 2026 – Dec 01, 2026: From USD 381
    17

    Tue

  • GUA–MDE, Nov 18, 2026 – Nov 20, 2026: From USD 453
    18

    Wed

  • GUA–MDE, Nov 19, 2026 – Jan 16, 2027: From USD 520
    19

    Thu

  • GUA–MDE, Nov 20, 2026 – Nov 23, 2026: From USD 453
    20

    Fri

  • GUA–MDE: cmp-view-offers-disclaimer. Check availability
    21

    Sat

  • GUA–MDE, Nov 22, 2026 – Nov 25, 2026: From USD 674
    22

    Sun

  • GUA–MDE, Nov 23, 2026 – Nov 27, 2026: From USD 661
    23

    Mon

  • GUA–MDE, Nov 24, 2026 – Nov 28, 2026: From USD 727
    24

    Tue

  • GUA–MDE: cmp-view-offers-disclaimer. Check availability
    25

    Wed

  • GUA–MDE, Nov 26, 2026 – Dec 01, 2026: From USD 674
    26

    Thu

  • GUA–MDE, Nov 27, 2026 – Dec 03, 2026: From USD 549
    27

    Fri

  • GUA–MDE, Nov 28, 2026 – Nov 28, 2026: From USD 799
    28

    Sat

    • FromUSD 381-USD 799

    *Restrictions apply; please see Terms & Conditions.

    Round-trip fares from Guatemala to Medellin

    USD
    Round-trip fares from Guatemala to Medellin
    From
    To
    Fare Type
    Dates
    Price
    Guatemala (GUA)Medellin (MDE)Round trip
    /
    Economy    		Mar 10, 2027 - Mar 10, 2027

    From

    USD 380

    Viewed 9 hours ago

    Guatemala (GUA)Medellin (MDE)Round trip
    /
    Economy    		Nov 05, 2026 - Nov 11, 2026

    From

    USD 381

    Viewed 10 hours ago

    Guatemala (GUA)Medellin (MDE)Round trip
    /
    Economy    		Feb 25, 2027 - Feb 28, 2027

    From

    USD 381

    Viewed 8 hours ago

    Guatemala (GUA)Medellin (MDE)Round trip
    /
    Economy    		Feb 15, 2027 - Feb 22, 2027

    From

    USD 381

    Viewed 22 hours ago

    Guatemala (GUA)Medellin (MDE)Round trip
    /
    Economy    		Nov 17, 2026 - Dec 01, 2026

    From

    USD 381

    Viewed 1 day ago

    *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
    *Restrictions apply; please see Terms & Conditions.

    Destination facts

    Destination airports
    • José María Córdova International Airport (MDE)
    Copa Airlines hub

    Hub of the Americas® in Panama

    Destination FAQs

    Which country or territory is the destination on this page in?

    Destination country or territory: Colombia.

    How do I identify the arrival airport?

    Check the name and code of the arrival airport in your selected itinerary.

    Where is the Hub of the Americas®?

    Copa Airlines’ Hub of the Americas® is in Panama.

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