Find Copa Airlines flights from Santo Domingo (SDQ) to Medellin (MDE) from USD268*
expand_more
expand_more
1 Passenger
expand_morePromo Code
expand_moretoday
today
Restrictions apply; please see Terms & Conditions.
Best prices on Santo Domingo to Medellin flights
location_on
location_on
Best airfares from Santo Domingo to Medellin flights
flight_takeoff
flight_land
USD
From | To | Fare Type | Dates | Price |
|---|---|---|---|---|
| Santo Domingo (SDQ) | Medellin (MDE) | Round trip / Economy | Feb 08, 2026 - Feb 16, 2026 | From USD268 Viewed 1 day ago |
| Santo Domingo (SDQ) | Medellin (MDE) | Round trip / Economy | Feb 06, 2026 - Feb 11, 2026 | From USD268 Viewed 18 hours ago |
| Santo Domingo (SDQ) | Medellin (MDE) | Round trip / Economy | Apr 02, 2026 - Apr 06, 2026 | From USD268 Viewed 19 hours ago |
| Santo Domingo (SDQ) | Medellin (MDE) | Round trip / Economy | Feb 12, 2026 - Feb 16, 2026 | From USD268 Viewed 19 hours ago |
| Santo Domingo (SDQ) | Medellin (MDE) | Round trip / Economy | Jan 26, 2026 - Jan 29, 2026 | From USD268 Viewed 1 day ago |
*Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
*Restrictions apply; please see Terms & Conditions.
Our App
Download the Copa Airlines App now and buy tickets, manage your reservations, access to your ConnectMiles account and much more.
Subscribe and save!
Subscribe and be one of the first to know about our exclusive fares, promotions and last minute offers.
Subscribe