Find Copa Airlines flights from Santo Domingo (SDQ) to Medellin (MDE) from USD 298*

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Best prices on Santo Domingo to Medellin flights

Aug 2026
FromUSD 298*
Viewed 1 day ago
Round trip/Economy
Sep 2026
FromUSD 298*
Viewed 1 day ago
Round trip/Economy
Oct 2026
FromUSD 298*
Viewed 19 hours ago
Round trip/Economy
cmp-daily-histogram-bars-legend-min-price-aria-label USD 298
cmp-daily-histogram-bars-legend-max-price-aria-label USD 423
Displaying fares for August-2026
  • SDQ–MDE, Aug 22, 2026 – Aug 26, 2026: From USD 423
    22

    Sat

    AUG

  • SDQ–MDE, Aug 23, 2026 – Aug 26, 2026: From USD 423
    23

    Sun

  • SDQ–MDE: cmp-view-offers-disclaimer. Check availability
    24

    Mon

  • SDQ–MDE, Aug 25, 2026 – Aug 27, 2026: From USD 423
    25

    Tue

  • SDQ–MDE, Aug 26, 2026 – Aug 31, 2026: From USD 349
    26

    Wed

  • SDQ–MDE, Aug 27, 2026 – Aug 31, 2026: From USD 349
    27

    Thu

  • SDQ–MDE, Aug 28, 2026 – Sep 04, 2026: From USD 298
    28

    Fri

  • SDQ–MDE: cmp-view-offers-disclaimer. Check availability
    29

    Sat

  • SDQ–MDE: cmp-view-offers-disclaimer. Check availability
    30

    Sun

  • SDQ–MDE, Aug 31, 2026 – Sep 11, 2026: From USD 298
    31

    Mon

  • SDQ–MDE: cmp-view-offers-disclaimer. Check availability
    01

    Tue

    SEP

  • SDQ–MDE, Sep 02, 2026 – Sep 08, 2026: From USD 298
    02

    Wed

  • SDQ–MDE, Sep 03, 2026 – Sep 07, 2026: From USD 388
    03

    Thu

  • SDQ–MDE, Sep 04, 2026 – Sep 08, 2026: From USD 388
    04

    Fri

  • SDQ–MDE, Sep 05, 2026 – Sep 14, 2026: From USD 298
    05

    Sat

  • SDQ–MDE, Sep 06, 2026 – Sep 14, 2026: From USD 298
    06

    Sun

  • SDQ–MDE, Sep 07, 2026 – Sep 12, 2026: From USD 298
    07

    Mon

  • SDQ–MDE, Sep 08, 2026 – Sep 12, 2026: From USD 298
    08

    Tue

  • SDQ–MDE, Sep 09, 2026 – Sep 14, 2026: From USD 298
    09

    Wed

  • SDQ–MDE, Sep 10, 2026 – Sep 14, 2026: From USD 298
    10

    Thu

  • SDQ–MDE: cmp-view-offers-disclaimer. Check availability
    11

    Fri

  • SDQ–MDE, Sep 12, 2026 – Sep 14, 2026: From USD 298
    12

    Sat

  • SDQ–MDE: cmp-view-offers-disclaimer. Check availability
    13

    Sun

  • SDQ–MDE: cmp-view-offers-disclaimer. Check availability
    14

    Mon

  • SDQ–MDE, Sep 15, 2026 – Sep 18, 2026: From USD 298
    15

    Tue

  • SDQ–MDE: cmp-view-offers-disclaimer. Check availability
    16

    Wed

  • SDQ–MDE, Sep 17, 2026 – Sep 21, 2026: From USD 298
    17

    Thu

  • SDQ–MDE, Sep 18, 2026 – Sep 26, 2026: From USD 298
    18

    Fri

  • SDQ–MDE: cmp-view-offers-disclaimer. Check availability
    19

    Sat

  • SDQ–MDE: cmp-view-offers-disclaimer. Check availability
    20

    Sun

  • SDQ–MDE, Sep 21, 2026 – Sep 27, 2026: From USD 310
    21

    Mon

    • FromUSD 298-USD 423

    *Restrictions apply; please see Terms & Conditions.

    Best airfares from Santo Domingo to Medellin flights

    USD
    Best airfares from Santo Domingo to Medellin flights
    From
    To
    Fare Type
    Dates
    Price
    Santo Domingo (SDQ)Medellin (MDE)Round trip
    /
    Economy    		Oct 23, 2026 - Oct 31, 2026

    From

    USD 298

    Viewed 22 hours ago

    Santo Domingo (SDQ)Medellin (MDE)Round trip
    /
    Economy    		Nov 05, 2026 - Nov 10, 2026

    From

    USD 298

    Viewed 21 hours ago

    Santo Domingo (SDQ)Medellin (MDE)Round trip
    /
    Economy    		Sep 06, 2026 - Sep 14, 2026

    From

    USD 298

    Viewed 1 day ago

    Santo Domingo (SDQ)Medellin (MDE)Round trip
    /
    Economy    		Sep 05, 2026 - Sep 14, 2026

    From

    USD 298

    Viewed 1 day ago

    Santo Domingo (SDQ)Medellin (MDE)Round trip
    /
    Economy    		Sep 17, 2026 - Sep 21, 2026

    From

    USD 298

    Viewed 1 day ago

    *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.
    *Restrictions apply; please see Terms & Conditions.

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